Author: Veronika R. Meyer
Publisher: John Wiley & Sons
ISBN: 3527659129
Category : Science
Languages : en
Pages : 224
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Book Description
The third edition of this popular problem-solving guide for this widely-used method includes eleven completely new examples and several updated ones, adding up to 100 contributions about pitfalls and errors in HPLC. Each example is presented on a double page with the text on the left-hand and a fi gure on the right-hand side, true to the motto 'a picture says more than a thousand words'. In addition, the author presents essential fundamentals as well as helpful strategies, such as equipment tests or quality assurance processes. New in this edition * Variability of the standard deviation * Infl uence of the acid type and concentration in the eluent * Water as an unintentional additive in the mobile phase * Inadequate purity of mobile phase water * Incomplete degassing * Inadequate stabilization of the extraction solvent * Tailing of phosphate compounds in the presence of steel * Different detection properties of diastereomers * Detector overload in ELSD * System suitability test * From repeatability to reproducibility A must-have resource for all users - showing how to use HPLC efficiently and obtain reliable results.
Author: Veronika R. Meyer
Publisher: John Wiley & Sons
ISBN: 3527659129
Category : Science
Languages : en
Pages : 224
View
Book Description
The third edition of this popular problem-solving guide for this widely-used method includes eleven completely new examples and several updated ones, adding up to 100 contributions about pitfalls and errors in HPLC. Each example is presented on a double page with the text on the left-hand and a fi gure on the right-hand side, true to the motto 'a picture says more than a thousand words'. In addition, the author presents essential fundamentals as well as helpful strategies, such as equipment tests or quality assurance processes. New in this edition * Variability of the standard deviation * Infl uence of the acid type and concentration in the eluent * Water as an unintentional additive in the mobile phase * Inadequate purity of mobile phase water * Incomplete degassing * Inadequate stabilization of the extraction solvent * Tailing of phosphate compounds in the presence of steel * Different detection properties of diastereomers * Detector overload in ELSD * System suitability test * From repeatability to reproducibility A must-have resource for all users - showing how to use HPLC efficiently and obtain reliable results.
Author: Veronika Meyer
Publisher: Wiley-VCH
ISBN:
Category : Science
Languages : en
Pages : 208
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Book Description
The complexity of the HPLC method allows on one side a wide variety of usage. On the other side it is also a source of possible errors. This book does not only list them, but illustrate them with concrete examples. The topics were presented in a clearly arranged style: a brief text with a corresponding figure. Chemists and laboratory assistants get here numerous hints how correct and reliable results could be transposed in daily laboratory work.
Author: Günter J. Eppert
Publisher:
ISBN: 9783000108082
Category :
Languages : en
Pages : 150
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Book Description
Author: Stavros Kromidas
Publisher: John Wiley & Sons
ISBN: 3527694978
Category : Science
Languages : en
Pages : 384
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Book Description
How can I use my HPLC/UHPLC equipment in an optimal way, where are the limitations of the technique? These questions are discussed in detail in the sequel of the successful "HPLC Expert" in twelve chapters written by experts in the respective fields. The topics encompass - complementary to the first volume - typical HPLC users' problems and questions such as gradient optimization and hyphenated techniques (LC-MS). An important key aspect of the book is UHPLC: For which analytical problem is it essential, what should be considered? Besides presentation of latest developments directly from the main manufacturers, also UHPLC users and independent service engineers impart their knowledge. Consistent with the target groups, the level is advanced, but the emphasis is on practical applications.
Author: Chunlong Zhang
Publisher: John Wiley & Sons
ISBN: 0470120673
Category : Science
Languages : en
Pages : 456
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Book Description
An integrated approach to understanding the principles of sampling, chemical analysis, and instrumentation This unique reference focuses on the overall framework and why various methodologies are used in environmental sampling and analysis. An understanding of the underlying theories and principles empowers environmental professionals to select and adapt the proper sampling and analytical protocols for specific contaminants as well as for specific project applications. Covering both field sampling and laboratory analysis, Fundamentals of Environmental Sampling and Analysis includes: A review of the basic analytical and organic chemistry, statistics, hydrogeology, and environmental regulations relevant to sampling and analysis An overview of the fundamentals of environmental sampling design, sampling techniques, and quality assurance/quality control (QA/QC) essential to acquire quality environmental data A detailed discussion of: the theories of absorption spectroscopy for qualitative and quantitative environmental analysis; metal analysis using various atomic absorption and emission spectrometric methods; and the instrumental principles of common chromatographic and electrochemical methods An introduction to advanced analytical techniques, including various hyphenated mass spectrometries and nuclear magnetic resonance spectroscopy With real-life case studies that illustrate the principles plus problems and questions at the end of each chapter to solidify understanding, this is a practical, hands-on reference for practitioners and a great textbook for upper-level undergraduates and graduate students in environmental science and engineering.
Author: George Lunn
Publisher: John Wiley & Sons
ISBN: 0471711675
Category : Science
Languages : en
Pages : 640
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Book Description
An indispensable resource for busy researchers Your time is valuable-too valuable to spend hunting through thetechnical literature in search of the right HPLC assay techniquesfor your projects. With HPLC Methods for Recently ApprovedPharmaceuticals, you'll quickly identify and replicate the idealprocedures for your project needs, without having to refer tooriginal source publications. More of your time can then be spentin the lab, not the library. Covering the relevant world literature through 2003, this bookpicks up where Dr. Lunn's acclaimed HPLC Methods for PharmaceuticalAnalysis left off. It arms you with established HPLC assaytechniques for hundreds of newly approved drugs, as well as drugsfor which assay methods were only recently developed. Combiningdetailed descriptions of procedures with specially annotatedreferences, this practical handbook gives you: * HPLC methods for 390 commonly prescribed pharmaceuticalcompounds * Various procedures for each drug listed together-making it easyto mix and match for customized approaches * Methods for drugs in biological fluids and for bulk andformulated drugs * Chemical structures, molecular weights and formulas, and CASRegistry Numbers * Cross-references to The Merck Index * Retention times of other drugs that can be assayed using the samemethods
Author: Paul C. Sadek
Publisher: John Wiley & Sons
ISBN: 0471678805
Category : Science
Languages : en
Pages : 240
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Book Description
Author: Veronika R. Meyer
Publisher: John Wiley & Sons
ISBN: 0470682183
Category : Science
Languages : en
Pages : 428
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Book Description
Jump into the HPLC adventure! Three decades on from publication of the 1st German edition of Veronika Meyer's book on HPLC, this classic text remains one of the few titles available on general HPLC aimed at practitioners. New sections on the following topics have been included in this fifth edition: Comparison of HPLC with capillary electrophoresis How to obtain peak capacity van Deemter curves and other coherences Hydrophilic interaction chromatography Method transfer Comprehensive two-dimensional HPLC Fast separations at 1000 bar HPLC with superheated water In addition, two chapters on the instrument test and troubleshooting in the appendix have been updated and expanded by Bruno E. Lendi, and many details have been improved and numerous references added. A completely new chapter is presented on quality assurance covering: Is it worth the effort? Verification with a second method Method validation Standard operating procedures Measurement uncertainty Qualifications, instrument test, and system suitability test The quest for quality Reviews of earlier editions "That this text is written by an expert in both the practice and teaching of HPLC is evident from the first paragraph....not only an enjoyable, fascinating and easy read, but a truly excellent text that has and will serve many teachers, students and practitioners very well." —The Analyst “…provides essential information on HPLC for LC practitioners in academia, industry, government, and research laboratories…a valuable introduction." - American Journal of Therapeutics
Author: Joachim Ermer
Publisher: John Wiley & Sons
ISBN: 3527604472
Category : Science
Languages : en
Pages : 418
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Book Description
Adopting a practical approach, the authors provide a detailed interpretation of the existing regulations (GMP, ICH), while also discussing the appropriate calculations, parameters and tests. The book thus allows readers to validate the analysis of pharmaceutical compounds while complying with both the regulations as well as the industry demands for robustness and cost effectiveness. Following an introduction to the basic parameters and tests in pharmaceutical validation, including specificity, linearity, range, precision, accuracy, detection and quantitation limits, the text focuses on a life-cycle approach to validation and the integration of validation into the whole analytical quality assurance system. The whole is rounded off with a look at future trends. With its first-hand knowledge of the industry as well as regulating bodies, this is an invaluable reference for analytical chemists, the pharmaceutical industry, pharmaceutists, QA officers, and public authorities.
Author: Stefan Dhein
Publisher: Springer
ISBN: 3540265740
Category : Medical
Languages : en
Pages : 1010
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Book Description
Scientists working or planning to work in the field of cardiovascular research will welcome Methods in Cardiovascular Research as the reference book they have been waiting for. Not only general aspects of cardiovascular research are well presented but also detailed descriptions of methods, protocols and practical examples. Written by leading scientists in their field, chapters cover classical methods such as the Langendorff heart or working heart models as well as numerous new techniques and methods. Newcomers and experienced researchers alike will benefit from the troubleshooting guide in each chapter, the extensive reference lists for advanced reading and the great practical experience of the authors. Methods in Cardiovascular Research is a "must have" for anybody with an interest in cardiovascular research.
